Determination of Arbutin in Herbal Medicinal Products

Arbutin is the main active ingredient in many herbal medicinal products that have diuretic, antimicrobial, bactericidal, and antioxidant effects. Many of these are mixtures different substances. Therefore, approaches to quality control HMPs can vary significantly. The aim study was compare arbutin assay procedures used arbutin-containing products. Materials methods. Samples following were study: monocomponent Bearberry Leaf multicomponent Brusniver ® (herbal mixture, powder). test methods titrimetry, ultraviolet-visible spectrophotometry, high-performance liquid chromatography (HPLC). Results. authors compared five described monographs product files for HMPs. Conclusions. It has been established analysed cannot be interchangeably as equivalent methods; limits each specific procedure. Iodometric titration most labour- time-consuming method, determined endpoint a subjective assessment. Spectrophotometric do not require use an reference standard, but they give overestimated results HPLC titrimetry more selective, standards. recommended HMP visible spectrophotometry; titrimetric method replacement.